Here is our TruBrain review. In this review, we will be going over the TruBrain supplement to see if it can help benefit you! Some background information:

— TruBrain formula is made by UCLA Neuroscientists

— The supplement uses a good assortment of minerals, nutrients, and nootropics

— The supplement also uses synthetic nootropics

In this review, we will go over the ingredients to check the safety and effectiveness of TruBrain. Is it worth buying? Our team finds out!


  • Noopept is effective for increasing focus and working memory
  • Can be taken with or without food
  • Formulated by experts
  • Good use of nutrients, minerals, and nootropics


  • Uses synthetic nootropics that are not suitable for everyday use
  • Potential side effects from Centrophenoxine
  • Missing some nootropics that make up a high-quality supplement
  • No long-term nootropic ingredients in the formula
  • There are no substantial cholinergic’s in the formula 


TruBrain is a nootropic supplement that may boost your working memory, mental output, reduce brain fog, and lower stress. 

TruBrain has a good assortment of minerals, nutrients, and nootropics. 

However, the supplement should include more essential nootropic ingredients like; Citicoline, Bacopa Monnieri, Ginkgo Biloba, Alpha-GPC, Huperzine-A, and Phosphatidylserine. The dosages of the minerals, nutrients, and nootropics in this formula are decent.

We do not like that TruBrain uses Centrophenoxine in its formula, which may cause adverse side effects in some people. TruBrain uses synthetic nootropics that are not suitable for daily use. There is no substantial chlorogenic in the TruBrain formula, which makes it less effective when it comes to improving your memory function, focus, and mental clarity. We think there are better nootropic supplements currently on the market that will provide more noticeable cognitive benefits. 

About TruBrain

Claimed Benefits: Boosts working memory, mental “output”, reduces brain fog, and lowers stress.
Ingredients: Noopept, Uridine Monophosphate, Acetyl L-Carnitine, N-Acetyl Tyrosine, Centrophenoxine, Magnesium (magnesium glycinate), L-Theanine.
Manufacturer: TruBrain
Available at:,
Price: $69 for the first jar, $119 thereafter [Capsules], Box of 20 Personalized Drinks $55

TruBrain is a supplement that does a decent job of using minerals and nutrients. The formula claims to increase blood flow to the brain, improve the brain’s plasticity, boost mental output, overcome mental blocks, reduce brain fog, and enhance working memory.

You can get TruBrain in two versions: capsules and nootropic drinks. Both work to support your brain health and performance, with the drink being more convenient (and tastier!).

The brain supplement, however, lacks several essential nootropics like; Citicoline, Phosphatidylserine, Alpha-GPC, and Huperzine-A, to help improve and maximize its effectiveness.

TruBrain contains Centrophenoxine, which can potentially cause adverse effects. TruBrain should have used Cognizin Citicoline. The supplement uses synthetic nootropics that are not suitable for daily use. So, how will TruBrain work for you? Do the pros outweigh the cons? Let’s find out.

Dosage Instructions

For the best results, take three (3) capsules of TruBrain each morning, with or without food. 

*The bottle contains 90 capsules/1 month supply*

You can take TruBrain Personalized Drinks 1-2 per day with or without food; don’t drink too close to bedtime due to caffeine. TruBrain Sleep supplement should be taken once per day before bedtime.

*A single shot/drink is 30mL/1oz*


Here is a closer look at the ingredients in TruBrain:

Noopept – 20mg

Noopept is a synthetic nootropic that has a similar effect to Piracetam. Noopept may provide a mild cognitive boost. 

Noopept has a standard dose of 10-30mg. 

After supplementing Noopept, you may notice the neuroprotective effect that occurs. Noopept improves your working memory, enhances focus, and reduces anxiety. 

A daily nootropic like TruBrain should not contain a synthetic nootropic like Noopept. Prolonged use of Noopept may cause adverse effects.

Uridine Monophosphate 500mg

Uridine Monophosphate is a component of RNA that may improve your cognitive function, relieve nerve pain, depression and protect the heart. 

Uridine may restructure and strengthen your brain to help enhance memory and learning. 

A standard dose of Uridine Monophosphate or UMP is anywhere from 500-1,000mg. 

TruBrain contains 500mg of Uridine Monophosphate. This amount of Uridine Monophosphate is substantial and will show significant benefits. 


Acetyl-L-Carnitine – 500mg

Acetyl-L-Carnitine is used in nootropic supplements to enhance your cognitive performance, boost energy, and reduce fatigue. Its primary function is to improve your cognitive function and muscle growth. 

A standard dose of Acetyl-L-Carnitine is between 630-2,500mg.

The TruBrain supplement contains 500mg of ALCAR. A higher dose is needed to boost your cognitive and physical performance. This dose of ALCAR is not going to provide a noticeable increase in cognitive performance or mental energy.

Centrophenoxine – 250mg

Centrophenoxine is a cholinergic compound with a DMAE component that may reverse some signs of aging. 

Centrophenoxine is a more bioavailable form of DMAE. Centrophenoxine is not as effective as Alpha-GPC or Citicoline. Centrophenoxine like DMAE is more likely to cause side effects.

TruBrain would be a better nootropic if its formula contained Cognizin Citicoline.


Magnesium  – 200mg (50% RDI)

Magnesium is an essential mineral that has numerous functions in the body. Magnesium may reduce your nerve activity, reduce anxiety, relieve muscle tension, and allow for calmness. 

A 50% RDI dose of Magnesium that we see in TruBrain should help ease your stress, anxiety, provide clarity, focus, and relaxation. 

L-Theanine 200mg

L-Theanine is an amino acid found in tea that may help reduce stress, anxiety; and provide relaxation. L-Theanine may improve your mental function, sleep quality, and help reduce depression. 

A combination of L-Theanine and caffeine may enhance your attention and cognitive performance. 

The supplement TruBrain contains 200mg of L-Theanine. The ideal amount to help sharpen your focus and boost mental energy without the sudden crash or jitters. 

Here is a closer look at the ingredients in TruBrain Drinks:

The TruBrain drinks all have the same base formula; Noopept, Theanine, Magnesium, Centrophenoxine, and Uridine. Some TruBrain drinks contain 100mg of caffeine, which is a significant amount of a natural stimulant. 

TruBrain Extra contains 150mg of Adrafinil, which is a potent pharmaceutical drug that will keep you awake and alert for up to 24 hours at a time. We would not recommend mixing Adrafinil or better known as Modafinil, with, Noopept. We strongly discourage mixing Adrafinil with caffeine. 

TruBrain Sleep has a different formula that should improve your sleeping quality. TruBrain Sleep is not the best nootropic drink; it contains GABA and 5-HTP that are both ineffective.

Most of TruBrain drinks contain caffeine; some of the added ingredients are ineffective. TruBrain Extra is a nootropic drink; it has a potent nootropic drug that should not be in a daily supplement.

Our Commentary on TruBrain Ingredients

TruBrain is a decent supplement – you will definitely see some benefits from it. You may notice a partial boost in your focus, learning capacity, and memory function. 

That being said, TruBrain is nowhere near the best nootropic supplements on the market. 

TruBrain’s main problem is the use of substandard ingredients. TruBrain uses cheaper, side effect prone, less effective, less bioavailable, and synthetic ingredients. The supplement contains Centrophenoxine, a DMAE derivative. Centrophenoxine like DMAE is more likely to cause adverse effects; Alpha-GPC or Citicoline would have been a better choice.

TruBrain contains synthetic nootropic drugs that are unusual in see in nootropic supplements. The main ingredient in TruBrain is Noopept. Noopept is too potent for daily use and prolonged periods. 

TruBrain is missing several ingredients that we look for in high-quality nootropic supplements. TruBrain does not have ingredients to boost brain cell growth, encourage blood flow to the brain, potent antioxidants, or anything that would increase dopamine levels. 

TruBrain lacks the ingredients in top nootropics; we doubt it will provide the benefits the manufacturer claims. There are better nootropics currently on the market to enhance your focus, mental energy, memory, and learning.

User Reviews

“I read it helps with focus and memory as well. I’m studying for advanced technical certification. I was really hoping this product would help me focus and it has helped with the grind :). Maybe it’s all mental or placebo. I guess I’ll never know lolz. .I take with a cup of coffee every morning.” – Amber S

“I really like this supplement as it gives me a calm yet alert state of mind throughout the day. It practically eliminates any brain fog I may feel and gives me a smooth form of energy and focus for many hours on end!” – Royce F

“I am allergic to coffee, and black tea also tends to make me sick. But with chronic fatigue syndrome, I am desperate for something to perk me up and give me energy and mental clarity at work. These are absorbed quickly and seem to do the trick for energy. I doesn’t give me shakes or insomnia. I can always take more if I wish. And the ingredients are great without all the sugar and artificial crap of energy drinks. Not cheap tho.” – Reanna Sanger  


The cost of TruBrain capsules is $69 for the first jar purchased. Each jar after the initial purchase will cost $119 on the official website. On Amazon, you can find the TruBrain for $125.

*TruBrain contains 90 capsules/1 month supply*

TruBrain sells nootropic drinks that are 30mL/1 oz.

  • 10 Drinks is $35
  • 15 Drinks is $45
  • 20 Drinks is $55, and on Amazon, it’s $65.
  • 30 Drinks is $69
  • 60 Drinks is $135

The price of TruBrain is steep for the quality of the supplement. There are plenty of high-quality nootropics on the market for a more affordable price.

Side Effects

The supplement TruBrain is relatively safe for infrequent short-term use; the same goes for Noopept and Centrophenoxine. Centrophenoxine is more likely to cause some adverse effects.

TruBrain may cause headaches, brain fog, loss of focus, low mood, and muscle cramps if used daily for an extended period.

Conclusion to TruBrain Review

TruBrain is a relatively decent nootropic supplement that uses a good assortment of minerals, nutrients, and nootropics. TruBrain is missing several high-quality nootropic ingredients that would maximize its performance.  

The nootropic supplement uses Noopept. Noopept is effective for increasing focus and working memory. The main problem of TruBrain is the use of substandard ingredients. TruBrain uses cheaper, less effective, and synthetic nootropic drugs; and Centrophenoxine.

TruBrain is a decent nootropic supplement that may partially boost your focus, memory function, and learning capacity. But it won’t provide all the expected benefits from its claims. There are more potent nootropic supplements available on the market; that will enhance your focus, memory, learning, and mental energy. You’ll find that these supplements tend to use only natural ingredients, and in optimal doses.

A. P.

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